By J. W. Hadden (Eds.)
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Extra resources for Advances in Immunopharmacology. Proceeding of the Fourth International Conference on Immunopharmacology, Osaka, Japan, 16–19 May 1988
1987). E. Graham) Alan R. Liss, Inc. , Ikeuchi, J. and Nina, N. (1986). , Nakai, K. and Harada, Y. (1986). , Yoshizaki, T. and Ikeuchi, J. (1986). J. R. (1987). C. A. (1985). J. Immunol. D. A. (1985). J. Biol. Resp. Modif. , Dawson, Α. and Harada, Y. (1986). , Dawson, A. and Harada, Y. (1986). , Dawson, A. and Harada, Y. (1986). Kiso to Rinsho (in Japanese) 20, 4175-4179 Zbinden, G. (1987). E. Graham) Alan R. Liss, Inc. 143-159 Overview on Neuroimmunomodulation and a Possible Role for Serotonergic System K.
All monkeys receiving 500 ug/kg/day were sacrificed in extremis during the course of the 4-week study. Except for these decedents, all the monkeys in the other groups survived through the experimental period. Throughout the study, loose faeces, lethargy and subdued behavior were observed in animals given higher than 50 Ug/kg/day. Flaky dry skins were noted in monkeys receiving 25 ug/kg/day for 40 weeks, despite the remaining of good appetite. Haematological changes, such as anemia, thrombocytopenia, neutropenia and eosinophilia were found in the groups dosed at higher than 25 ug/kg/day.
Launay (1988). Hypothetical role of the serotonergic system in neuroimmunomo dulation: Preliminary molecular studies. nd immune systems. Ed. J. Hadden, K. Masek and G. NistTcoT^Pytagora Press, Milan, p. 00. , K. Masek, 0. Gulda, V . Ruzicka, M . Parant and L. Chedid (1984). Smooth muscle stimulation by an immunomodulatory compound muramyl dipeptide: does it involve serotoninergic system? Pharmacology. 29> 31-39. , S. Y. Feiten, S. L. Carlson, D . L. Bellinger and D . L. Feiten (1985). Involvement of peripheral and central Overview on Neuroimmunomodulation 45 catecholamine systems in neural-immune interactions.